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Registros recuperados: 8
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Cardiovascular actions of angiotensin-(1-7) BJMBR
Ferreira,A.J.; Santos,R.A.S..
Angiotensin-(1-7) (Ang-(1-7)) is now considered to be a biologically active member of the renin-angiotensin system. The functions of Ang-(1-7) are often opposite to those attributed to the main effector component of the renin-angiotensin system, Ang II. Chronic administration of angiotensin-converting enzyme inhibitors (ACEI) increases 10- to 25-fold the plasma levels of this peptide, suggesting that part of the beneficial effects of ACEI could be mediated by Ang-(1-7). Ang-(1-7) can be formed from Ang II or directly from Ang I. Other enzymatic pathways for Ang-(1-7) generation have been recently described involving the novel ACE homologue ACE2. This enzyme can form Ang-(1-7) from Ang II or less efficiently by the hydrolysis of Ang I to Ang-(1-9) with...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Angiotensin-(1-7) receptor Mas; Renin-angiotensin system; Cardiac function; Blood vessels; Angiotensin-converting enzyme 2; Transgenic models.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000400003
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Distribution of Arteriolovenous Vessels, Capillaries and eNOS Expression in the Bovine Corpus Luteum During the Estrous Cycle : a Possible Implication of Different Sensitivity by Luteal Phase to PGF2α in the Increase of Luteal Blood Flow OAK
SHIRASUNA, Koumei; ASAHI, Takayuki; SASAKI, Motoki; SHIMIZU, Takashi; MIYAMOTO, Akio; 白砂, 孔明; 佐々木, 基樹; 清水, 隆; 宮本, 明夫.
We have shown that luteal blood flow increases in the peripheral vasculature of the mature corpus luteum (CL) prior to the onset of luteolysis in response to prostaglandin F2α (PGF2α) in the cow, but this phenomenon does not occur in the early CL. We therefore hypothesize that this acute increase of luteal blood flow occurs by vasodilation of large blood vessels due to local release of nitric oxide (NO). In the present study, we characterized the CL vasculature together with endothelial NO synthase (eNOS) expression during the estrous cycle in the cow. Immunohistochemistry was used to quantify the number of arteriolovenous vessels (surrounded with smooth muscle actin-positive smooth muscle cells), capillaries (with von Willebrand Factor-positive...
Palavras-chave: Blood vessels; Corpus luteum; ENOS; Luteolysis.
Ano: 2010 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/2989
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Effects of low-intensity pulsed ultrasound exposure on rats tibia periosteum Anais da ABC (AABC)
Batista,Jaqueline Martins; Nakagaki,Wilson Romero; Soares,Evelise Aline; Camilli,José Angelo.
Abstract The periosteum is a rich source of osteoprogenitor cells and periosteal grafts can be used as an alternative method to replace bone grafts. The low-intensity pulsed ultrasound (LIPUS) has often been used as a noninvasive method to stimulate osteogenesis and reduce the fracture healing time. The aim of this study was to evaluate the effects of the ultrasound exposure on the rat tibia periosteum. Group I (7 animals) received LIPUS therapy on the left tibia for 7 days and group II (7 animals) on the left tibia for 14 days. After euthanasia, the tibias were processed. Number of periosteal cells and vessels and thickness of the periosteum were analyzed. The number of periosteal cells was higher in stimulated periosteum compared to controls at 7 and 14...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Tibia; Blood vessels; Periosteal cells; Periosteum; Low-intensity pulsed ultrasound.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000100901
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Evaluation of ovarian structures using computerized microtomography Anais da ABC (AABC)
PAULINI,FERNANDA; CHAVES,SACHA B.; RÔLO,JOSÉ LUIZ J.P.; AZEVEDO,RICARDO B. DE; LUCCI,CAROLINA M..
ABSTRACT Visualization and clear understanding of the ovarian structures are important in determining the stage of oestrus, helping to diagnose several pathologies and supporting advances in reproductive technologies. In this research, computerized microtomography (microCT) was used to explore and characterize the ovarian structure of seven mammalian species. Ovaries of rats, female dog, queens, cows, mares, sows and a female donkey were used. After microCT scanning, the same samples were prepared for histologic evaluation, used here as a validation criterion. It was possible to distinguish regions of the cortex and medulla, visualize the morphology and distribution of blood vessels, clearly observe corpus luteum and antral follicles, and visualize oocytes...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ovarian follicle; Blood vessels; Histology; Tomography; Ovary.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000502131
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In ovo administration of human recombinant leptin shows dose dependent angiogenic effect on chicken chorioallantoic membrane Biol. Res.
Manjunathan,Reji; Ragunathan,Malathi.
BACKGROUND: Leptin, the cytokine produced by white adipose tissue is known to regulate food energy homeostasis through its hypothalamic receptor. In vitro studies have demonstrated that leptin plays a major role in angiogenesis through binding to the receptor Ob-R present on ECs by stimulating and initiating new capillary like structures from ECs. Various in vivo studies indicate that leptin has diverse effect on angiogenesis. A few reports have showed that leptin exerts pro angiogenic effects while some suggested that it has antiangiogenic potential. It is theoretically highly important to understand the effect of leptin on angiogenesis to use as a therapeutic molecule in various angiogenesis related pathological conditions. Chicken chorio allantoic...
Tipo: Journal article Palavras-chave: Angiogenesis; HRL; Human Recombinant Leptin; CAM; Chorioallantoic membrane; ECs; Endothelial cells; VEGF; Vascular endothelial growth factor; MMP; Matrix metalloproteinase; Blood vessels; CD34.
Ano: 2015 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100029
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Morphometry and Vascularization of the Rabbit Kidneys (Oryctolagus cuniculus) International Journal of Morphology
Santos-Sousa,C. A; Stocco,A. V; Mencalha,R; Jorge,S. F; Abidu-Figueiredo,M.
Rabbits have been used as urologic models in many studies. The aim of this study was to characterize the renal morphology and anatomical variations of the renal pedicle in rabbit. The research ethics committee of Rio de Janeiro Federal Rural University approved this study. The animals were obtained from the university's necropsy unit. Dissections were performed in 50 adult rabbits, male and females, without macroscopic renal pathology. Kidney measurements were made with a digital caliper: length, width, and thickness. The length and origin of the renal arteries and main branches and length of the renal veins were also determined. The terminology of Nomina Anatomica Veterinaria was followed. The mean and standard deviation of the length of the right kidney...
Tipo: Journal article Palavras-chave: Blood vessels; Kidney; Measurements; Variability; Rabbit.
Ano: 2015 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000400017
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Renal artery in tufted capuchin monkey: structure and morphometry Biological Sciences
Mello, Josiane Medeiros de; Orsi, Antonio Marcos; Gomes, Célia Regina de Godoy; Spilla, Caio Sérgio Galina; Oliveira, José Américo de; Bilotti, Carolina Correia.
  The objective was to describe the structure of the renal artery in capuchin monkey at the level of the proximal and distal arterial segments. Morphometric analysis was performed referring to the thickness and quantification of tissue elements of the renal artery tunica media in both segments. Renal arteries of eight adult capuchin monkeys were collected for histological analysis of the two segments, being the proximal part branched from the abdominal aorta, and the distal part localized next to the renal hilus. The quantification of smooth muscle cells and connective elements was carried out in transversal sections of the two segments; for the tunica media, it was used the volume densities of smooth muscle cells, collagen and elastic fibers. Considering...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Anatomia e histologia vasos sanguineos mamíferos anatomy and histology; Blood vessels; Mammals..
Ano: 2018 URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/38801
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Role of endothelium in angiotensin II formation by the rat aorta and mesenteric arterial bed BJMBR
We investigated the angiotensin II (Ang II)-generating system by analyzing the vasoconstrictor effect of Ang II, angiotensin I (Ang I), and tetradecapeptide (TDP) renin substrate in the absence and presence of inhibitors of the renin-angiotensin system in isolated rat aortic rings and mesenteric arterial beds with and without functional endothelium. Ang II, Ang I, and TDP elicited a dose-dependent vasoconstrictor effect in both vascular preparations that was completely blocked by the Ang II receptor antagonist saralasin (50 nM). The angiotensin converting enzyme (ACE) inhibitor captopril (36 µM) completely inhibited the vasoconstrictor effect elicited by Ang I and TDP in aortic rings without affecting that of Ang II. In contrast, captopril (36 µM)...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Angiotensin II; Angiotensin converting enzyme; Renin-angiotensin system; Endothelium; Blood vessels; Captopril.
Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000500013
Registros recuperados: 8
Primeira ... 1 ... Última
 

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